Fracture-induced pain-like behaviours in a femoral fracture mouse model.
R MagnusdottirS GohinF Ter HeegdeM HopkinsonI F McNallyA FisherN UptonA BillintonChantal ChenuPublished in: Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA (2021)
Fractures in rodent models are highly painful in both sexes. This pain-like phenotype is prolonged and should be routinely considered in fracture healing studies as it can affect the study outcome. The anti-NGF alleviates fracture-induced mechanical pain.