Evaluation of serum levels of asprosin and other metabolic profiles in patients with idiopathic tonic-clonic generalized epilepsy on treatment with valproic acid.

Amir-Mohammad YaryariMehrdokht MazdehMojdeh MohammadiAlireza Rastgoo HaghiMasood GhiasianMaryam Mehrpooya

Published in: European journal of clinical pharmacology (2022)

Our finding suggested that elevated asprosin level might be one of the pathological mechanisms involved in the development of obesity, insulin resistance, and metabolic disturbances related to valproic acid treatment.

Keyphrases

insulin resistance
type diabetes
metabolic syndrome
adipose tissue
skeletal muscle
high fat diet induced
combination therapy
physical activity
body mass index
replacement therapy