Risk Factors for Intracerebral Hemorrhage: Genome-Wide Association Study and Mendelian Randomization Analyses.
Susanna C LarssonTherese HeskethDipender GillStephen BurgessQiqiang HePublished in: Stroke (2024)
locus contributes to ICH genetic susceptibility in European populations. Excess adiposity, elevated blood pressure, type 2 diabetes, and smoking were identified as the chief modifiable cardiometabolic and lifestyle factors for ICH.
Keyphrases
- genome wide association study
- type diabetes
- blood pressure
- insulin resistance
- cardiovascular disease
- metabolic syndrome
- brain injury
- glycemic control
- hypertensive patients
- smoking cessation
- weight loss
- genome wide
- heart rate
- physical activity
- copy number
- adipose tissue
- weight gain
- blood glucose
- genetic diversity
- body mass index
- gene expression
- skeletal muscle
- dna methylation