Activation of D1/D5 Receptors Ameliorates Decreased Intrinsic Excitability of Hippocampal Neurons Induced by Neonatal Blockade of NMDA Receptors.
Ernesto GriegoMelissa Hernández-FraustoLuis A MárquezLeonardo LaraCarolina López RubalcavaEmilio J GalvánPublished in: British journal of pharmacology (2021)
Our results offer a molecular and mechanistic explanation based on dysregulation of glutamatergic in addition to dopaminergic transmission that may contribute to the understanding of the cognitive deterioration associated with schizophrenia.