Neuromedin-U Mediates Rapid Activation of Airway Group 2 Innate Lymphoid Cells in Mild Asthma.

Xiaotian JuAkimichi NagashimaAnna Dvorkin-GhevaJennifer WattieKaren HowieChristiane WhetstoneMaral RanjbarRuth CusackReina DittaGuillaume ParéImran SatiaPaul M O'ByrneGail M Gauvreau Roma Sehmi

Published in: American journal of respiratory and critical care medicine (2024)

The NMU/NMUR1 axis stimulates rapid effects on ILC2, and maybe an important early activator of these cells in eosinophilic inflammatory responses in asthma.

Keyphrases

induced apoptosis
cell cycle arrest
chronic obstructive pulmonary disease
lung function
endoplasmic reticulum stress
cell death
allergic rhinitis
immune response
loop mediated isothermal amplification
quantum dots