Obesity, diabetes and their metabolic correlates in middle-aged adults with Down syndrome.
José A LuchsingerD PangS J Krinsky-McHaleN SchupfJ H LeeW SilvermanW B ZigmanPublished in: Journal of intellectual disability research : JIDR (2023)
The only metabolic correlate of obesity in middle-aged adults with Down syndrome was high leptin levels. Our findings are limited by non-fasting laboratory tests but suggest that middle-aged adults with Down syndrome do not have the adverse metabolic profile related to obesity found in adults without Down syndrome.