miR-101-5p suppresses trophoblast cell migration and invasion via modulating the DUSP6-ERK1/2 axis in preeclampsia.

Jiacheng XuJie WangMiaomiao ChenBingdi ChaoJie HeYuxiang BaiXiaofang LuoHongli LiuLumei XieYuelan TaoHongbo QiXin Luo

Published in: Journal of assisted reproduction and genetics (2023)

This study revealed that miR-101-5p inhibits the migration and invasion of HTR8/SVneo cells by regulating the DUSP6-ERK1/2 axis, providing a new molecular mechanism for the pathogenesis of PE.

Keyphrases

signaling pathway
induced apoptosis
pi k akt
single cell
cell cycle arrest
cell proliferation
cell therapy
stem cells
oxidative stress
cell death
pregnancy outcomes