Using instrumental variables to correct for bias in real-world cohort studies of the effects of disease-modifying treatment in MS.
Nils Iørgen Koch-HenriksenLau Caspar ThygesenPer Soelberg SørensenMelinda MagyariPublished in: Multiple sclerosis (Houndmills, Basingstoke, England) (2023)
The use of IVs eliminates indication bias and confirms that treatment is effective in delaying disability. IVs could, under some circumstances, be an alternative to marginal structural models.