Transition to Dolutegravir Is Associated With an Increase in the Rate of Body Mass Index Change in a Cohort of Virally Suppressed Adolescents.
Neil ThivalapillTandzile SimelaneNobuhle MthethwaSandile DlaminiBhekumusa LukheleVelephi OkelloH Lester KirchnerAnna M MandalakasAlexander W KayPublished in: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America (2021)
Transition to DTG in virally suppressed adolescents (aged 10-19 years) is associated with an increase in the rate of BMI change. Female adolescents may experience a larger change than males. Further investigation is required to elucidate the mechanism that underlies these observations and to assess how DTG impacts BMI in adolescents following longer durations of treatment.