Homocysteine, rather than age of onset, is a better predictor for cognitive function in older adults with bipolar disorder.
Pao-Huan ChenHsing-Cheng LiuMong-Liang LuChun-Hsin ChenChing-Jui ChangWei-Che ChiuI-Wen SunShen-Ing LiuShang-Ying TsaiChih-Chiang ChiuRobert StewartPublished in: International journal of geriatric psychiatry (2019)
Among older people with bipolar disorder, LOBD is not associated with more cognitive dysfunction in this study. However, higher serum homocysteine levels were significantly associated with worse cognitive performance in this particular group. Clinicians therefore have to pay attention to the cognitive function in older bipolar patients with higher levels of homocysteine.