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Aminoglycoside- and glycopeptide-induced ototoxicity in children: a systematic review.

F A DiepstratenAlexander E HoetinkM van GrotelA D R HuitemaR J StokroosM M van den Heuvel-EibrinkA J M Meijer
Published in: JAC-antimicrobial resistance (2021)
In children the reported occurrence of aminoglycoside/glycopeptide ototoxicity highly varies and seems to depend on the diagnosis, aminoglycoside subtype and use of co-administered medication. More research is needed to investigate the prevalence and determinants of aminoglycoside/glycopeptide ototoxicity. Our results indicate that age-dependent audiological examination may be considered for children frequently treated with aminoglycosides/glycopeptides especially if combined with other ototoxic medication.
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