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Insights into the origin of metazoan multicellularity from predatory unicellular relatives of animals.

Denis V TikhonenkovElisabeth HehenbergerAnton S EsaulovOlga I BelyakovaYuri A MazeiAlexander P MylnikovPatrick J Keeling
Published in: BMC biology (2020)
The feeding modes of the ancestral metazoan may have been more complex than previously thought, including not only bacterial prey, but also larger eukaryotic cells and organic structures. The ability to feed on large eukaryotic prey could have been a powerful trigger in the formation and development of both aggregative (e.g., joint feeding, which also implies signaling) and clonal (e.g., hypertrophic growth followed by palintomy) multicellular stages that played important roles in the emergence of multicellular animals.
Keyphrases
  • induced apoptosis
  • cell cycle arrest
  • high resolution
  • endoplasmic reticulum stress
  • oxidative stress
  • signaling pathway