A M1 muscarinic acetylcholine receptor positive allosteric modulator improves pathology and cognitive deficits in female APPswe/PSEN1ΔE9 mice.
Khaled S Abd-ElrahmanShaarika SarasijaTash-Lynn L ColsonStephen S G FergusonPublished in: British journal of pharmacology (2021)
Using M1 mAChR PAMs can be a viable disease-modifying approach that should be exploited clinically to slow AD in women.