Structural Brain Alterations in Community Dwelling Individuals with Chronic Joint Pain.
M de KruijfD BosF J P M HuygenWiro J NiessenH TiemeierAlbert HofmanA G UitterlindenMeike W VernooijMohammad Arfan IkramJ B J van MeursPublished in: AJNR. American journal of neuroradiology (2015)
The primary identified brain areas, the temporal and frontal lobes and the hippocampus, indicated involvement of emotional processing. The volumetric differences found indicated a sex-specific neuroplasticity in chronic pain. These results emphasized sex-specific and multidisciplinary pain treatment.