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Hidradenitis suppurativa in a patient with Warkany syndrome: Sustainability of adalimumab treatment.

Laura AtzoriFilippo BonatoLuca PilloniFranco Rongioletti
Published in: Dermatologic therapy (2019)
Mental retardation is a potential limitation to self-administration of innovative biologic treatment, which is otherwise very effective for devastating chronic inflammatory conditions, such as hidradenitis suppurativa (HS). We report our successful experience with a 34-year-old woman, who was genetically affected by Warkany syndrome, which causes intellectual disability. This patient was unable to maintain long-term antibiotic regimen and was disappointed by the limited results in her 12 years' history of painful draining fistulae and abscesses; however, she enthusiastically adhered to adalimumab 40 mg/once weekly treatment. After 52 weeks, treatment compliance is excellent, the patient is satisfied with the HS improvements, and no adverse effects have been reported.
Keyphrases
  • hidradenitis suppurativa
  • intellectual disability
  • case report
  • rheumatoid arthritis
  • autism spectrum disorder
  • mental health
  • combination therapy
  • drug induced