RNF8 promotes efficient DSB repair by inhibiting the pro-apoptotic activity of p53 through regulating the function of Tip60.

Hongyu ChenJin ShanJialing LiuYunpeng FengYueshuang KeWenjing QiWenguang LiuXianlu Zeng

Published in: Cell proliferation (2020)

Taken together, these findings suggested that RNF8 promotes efficient DSB repair by inhibiting the pro-apoptotic activity of p53 through regulating the function of Tip60.

Keyphrases

anti inflammatory
cell death
signaling pathway
dna damage response