Evaluation of a DNA demethylating agent in combination with all-trans retinoic acid for IDH1-mutant gliomas.

Marina da Costa RosaAlex Shimura YamashitaGregory J Riggins

Published in: Neuro-oncology (2021)

Use of DNA demethylating agent in combination with retinoids shows promise, but further optimization and preclinical studies are required for treatment of intracranial IDH-mutant gliomas.

Keyphrases

wild type
high grade
low grade
circulating tumor
cell free
single molecule
nucleic acid
big data
cell therapy
bone marrow
case control
deep learning