Prenatal diagnosis of susceptibility loci for neurodevelopmental disorders - genetic counseling and pregnancy outcome in 57 cases.
Lutgarde GovaertsMalgorzata Ilona SrebniakKarin DiderichMarieke JoostenSam RiedijkMaarten KnapenAttie GoDimitri PapatsonisKatja de GraafToon ToolenaarSanne van der SteenGido HuijbregtsJeroen KnijnenburgFemke de VriesDiane Van OpstalRobert-Jan GaljaardPublished in: Prenatal diagnosis (2016)
The diagnosis of a SL did not seem to be a reason for termination of pregnancy. Most patients were able to cope with the uncertainty and were interested in both prenatal and postnatal actionability of SL. Long-term follow-up is crucial to assess the actual risks for neurodevelopmental disorders, especially in families with unremarkable history. © 2016 John Wiley & Sons, Ltd.