Biochemical Urine Testing of Medication Adherence and Its Association With Clinical Markers in an Outpatient Population of Type 2 Diabetes Patients: Analysis in the DIAbetes and LifEstyle Cohort Twente (DIALECT).
Jelle M BeerninkMilou M OosterwijkKamlesh Khunti F MedSciAshley E TatePrashanth PatelJob F M van BovenHiddo J Lambers HeerspinkStephan J L BakkerGerjan NavisRoos M NijboerGozewijn D LavermanPublished in: Diabetes care (2021)
Although medication adherence of real-world type 2 diabetes patients managed in specialist care was relatively high, the prevalence of microvascular and macrovascular complications was significantly higher in nonadherent patients, and treatment targets were reached less frequently. This emphasizes the importance of objective detection and tailored interventions to improve adherence.