Interest of chromosomal microarray analysis in the prenatal diagnosis of fetal intrauterine growth restriction.

Stephanie BrunPerrine PennamenAurelien MattuizziFrederic CoatlevenMarie Laure VuillaumeDidier LacombeBenoit ArveilerJérôme Toutain Caroline Rooryck

Published in: Prenatal diagnosis (2018)

Our study highlights the added value of CMA in the case of associated fetal IUGR with an incremental yield of 6.1% (4/65) over karyotyping. No pathogenic CNVs were reported in the isolated fetal IUGR group. More studies must be conducted to determine when and whether CMA would be wisely indicated in this population.

Keyphrases

gene expression
copy number