Stereochemical Assignment of the 36-Membered Macrolide Ring Portion of Poecillastrin C.

Raku IrieYuki HitoraRyuichi WatanabeHugh ClarkYu SuyamaShinji SekiyaToshiyuki SuzukiKentaro TakadaShigeki MatsunagaSeijiro Hosokawa Masato Oikawa

Published in: Organic letters (2024)

Absolute configuration at 12 stereocenters in the 36-membered macrocyclic ring portion of poecillastrin C ( 1 ) was disclosed by chemical degradation and NMR analyses of 1 , chemical synthesis, and molecular modeling techniques.

Keyphrases

magnetic resonance
high resolution
mass spectrometry