Double overexpression of miR-19a and miR-20a in induced pluripotent stem cell-derived mesenchymal stem cells effectively preserves the left ventricular function in dilated cardiomyopathic rat.
Jiunn-Jye SheuHan-Tan ChaiPei-Hsun SungJohn Y ChiangTien-Hung HuangPei-Lin ShaoShun-Cheng WuHon-Kan YipPublished in: Stem cell research & therapy (2021)
iPS-MSCdOex-mIRs therapy was superior to iPS-MSC therapy for preserving LV function in DCM rat.
Keyphrases
- cell proliferation
- stem cells
- long non coding rna
- left ventricular
- long noncoding rna
- oxidative stress
- heart failure
- diabetic rats
- high glucose
- mitral valve
- drug induced
- cell therapy
- aortic stenosis
- cardiac resynchronization therapy
- coronary artery disease
- acute coronary syndrome
- bone marrow
- transcatheter aortic valve replacement