Associations of the vasoactive peptides CT-proET-1 and MR-proADM with incident type 2 diabetes: results from the BiomarCaRE Consortium.
Chaterina SujanaVeikko V SalomaaFrank KeeJochen SeisslerPekka JousilahtiCharlotte NevilleCornelia ThenWolfgang KoenigKari KuulasmaaJaakko ReinikainenStefan BlankenbergTanja ZellerChristian HerderUlrich Robert MansmannAnnette PetersBarbara Thorandnull nullPublished in: Cardiovascular diabetology (2022)
Higher concentrations of CT-proET-1 and MR-proADM are associated with incident type 2 diabetes, but our Mendelian randomisation analysis suggests a probable causal link for CT-proET-1 only. The association of MR-proADM seems to be modified by body composition.
Keyphrases
- contrast enhanced
- body composition
- type diabetes
- magnetic resonance imaging
- computed tomography
- image quality
- cardiovascular disease
- dual energy
- magnetic resonance
- bone mineral density
- glycemic control
- resistance training
- positron emission tomography
- insulin resistance
- metabolic syndrome
- adipose tissue
- skeletal muscle
- amino acid
- high intensity
- pet ct