High Density of CD16+ Tumor-Infiltrating Immune Cells in Recurrent Ovarian Cancer Is Associated with Enhanced Responsiveness to Chemotherapy and Prolonged Overall Survival.
Alexandros LalosOrnella NeriCaner ErcanAlexander WilhelmSebastian StaubliAlberto PosabellaBenjamin WeixlerLuigi TerraccianoSalvatore PiscuoglioSylvia StadlmannGiulio C SpagnoliRaoul A DroeserGad SingerPublished in: Cancers (2021)
The high density of CD16-expressing TICs in recurrent ovarian cancer is associated with a better RFS and OS, thereby suggesting a previously unsuspected interaction between standard OC chemotherapy and immune cell infiltration.