Measuring Serum Vedolizumab and Vedolizumab Antibodies: Comparison of Commercial Assays with the Vedolizumab Clinical Development Assay.

Niels Vande CasteeleLili YangIwona DoblerChristian AgbotonTeresa McRorie OsbornAjit SuriDirk LindnerGlennda M Smithson

Published in: Therapeutic drug monitoring (2023)

All 5 commercial assays are suitable for VDZ therapeutic monitoring and ADA testing. However, the absolute values from the reference assays and the different commercial assays were not comparable, indicating that the same assay must be used for repeated monitoring of VDZ serum concentrations.

Keyphrases

high throughput
ulcerative colitis
patients with inflammatory bowel disease