Adult H3K27M mutated thalamic glioma patients display a better prognosis than unmutated patients.
Stéphan GrimaldiVincent HarlayRomain AppayCéline BequetGrégorio PetrirenaChantal CampelloMaryline BarriéDidier AutranSébastien BoissonneauThomas GraillonDominique Figarella-BrangerIsabelle NanniOlivier ChinotEmeline TabouretPublished in: Journal of neuro-oncology (2022)
Thalamic adult glioma differs from bithalamic glioma in children with regards to its clinical, radiological and molecular profiles. Long-term survival is observed in young patients with limited symptoms and H3K27M mutation. A larger prospective cohort is needed to validate these findings.