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Rapamycin Reduces Cervical Cancer Cells Viability in Hypoxic Condition: Investigation of the Role of Autophagy and Apoptosis.

Davood RezazadehAmir Hossein NorooznezhadKamran MansouriMozhgan JahaniAli MostafaieMohammad Hossein MohammadiMohammad Hossein Modarressi
Published in: OncoTargets and therapy (2020)
These findings provide a new evidence that rapamycin may inhibit hypoxic HeLa cell proliferation through the trigger of programmed cell death, facilitating the development of novel anti-cancer therapy.
Keyphrases
  • cell cycle arrest
  • cell death
  • pi k akt
  • endoplasmic reticulum stress
  • induced apoptosis
  • cell proliferation
  • signaling pathway
  • oxidative stress
  • cell cycle