Synthesis and Antiprotozoal Profile of 3,4,5-Trisubstituted Isoxazoles.

Fernanda Andreia RosaSamara Mendes de Souza MeloKarlos Eduardo PianoskiJulia PolettoMariellen Guilherme Dos SantosMichael Jackson Vieira da SilvaDanielle Lazarin-BidóiaHélito VolpatoSidnei MouraCelso Vataru Nakamura

Published in: ChemistryOpen (2021)

Invited for this month's cover picture is the group of Prof. Fernanda Andreia Rosa at the State University of Maringá (Brazil). The cover picture shows the contribution of the SINTHET research group to the synthesis and discovery of new antiprotozoal compounds. The synthetic methodology allowed the construction of 60 new isoxazole derivatives with structural variations on the 3-, 4-, and 5-positions. The authors acknowledge Ms. Jeniffer do Nascimento Ascencio Camargo and Ms. Julia Caroline Manzano Willig for the Cover picture creation. Read the full text of their Full Paper at 10.1002/open.202100141.

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