Nintedanib-Induced Colitis Can Mimic Inflammatory Bowel Disease.
Tarek OdahChristian KarimeJana G HashashFrancis A FarrayePublished in: ACG case reports journal (2024)
Nintedanib is a medication that has been increasingly used for treatment of idiopathic and progressive pulmonary fibrosis. In this case series, we describe 3 patients with colitis symptoms associated with nintedanib use. Nintedanib discontinuation resulted in symptomatic resolution in all patients. Budesonide decreased symptoms in 1 patient. Clinicians should be vigilant in taking a thorough medication history and include nintedanib as a cause for gastrointestinal symptoms including colitis.
Keyphrases
- idiopathic pulmonary fibrosis
- interstitial lung disease
- pulmonary fibrosis
- end stage renal disease
- systemic sclerosis
- healthcare
- ejection fraction
- newly diagnosed
- sleep quality
- multiple sclerosis
- chronic kidney disease
- ulcerative colitis
- peritoneal dialysis
- prognostic factors
- rheumatoid arthritis
- emergency department
- adverse drug
- palliative care
- patient reported outcomes
- single molecule
- smoking cessation
- drug induced