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In-vitro and in-vivo antimalarial activity of caffeic acid and some of its derivatives.

Sylvain G AlsonOlivia JansenEwa CieckiewiczHajatiana RakotoarimananaHerintsoa RafatroGilles DegottePierre FrancotteMichel Frédérich
Published in: The Journal of pharmacy and pharmacology (2018)
Our study provides evidence for an antimalarial potential of caffeic acid derivatives which are common in several medicinal plants traditionally used against malaria. It also demonstrates the possibility to use such derivatives in the treatment of malaria.
Keyphrases
  • plasmodium falciparum
  • structure activity relationship
  • risk assessment
  • combination therapy