Predictors of Sentinel Lymph Node Metastasis in Very Thin Invasive Melanomas.
Hanna H KakishJames SunDavid X ZhengFasih Ali AhmedMohamedraed ElshamiAlexander W LoftusLee M OcuinJohn B AmmoriRichard S HoehnJeremy S BordeauxLuke D RothermelPublished in: The British journal of dermatology (2023)
Nodal positivity has prognostic significance for very thin melanomas. In our cohort, the rate of nodal positivity was 5% overall in these patients who underwent SLNB. Specific tumor factors (e.g. lymphovascular invasion, ulceration, mitoses, nodular subtype) were associated with higher rates of SLN metastases and should be used to guide clinicians in choosing which patients will benefit from sentinel lymph node biopsy.