Assessing the commutability of candidate reference materials for the harmonization of neurofilament light measurements in blood.
Ulf AndreassonJohan GobomVincent DelatourGuy AuclairYoav NoamStephen LeeJason WenAndreas JerominBurak ArslanAleksandra MaceskiEline WillemseHenrik ZetterbergJens KuhleKaj BlennowPublished in: Clinical chemistry and laboratory medicine (2023)
The results from this first commutability study on NfL in serum/plasma showed that it is feasible to create a CRM for NfL in blood and that spiking should be done using CSF rather than with recombinant human NfL protein.