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Antimuscarinic actions on bladder urothelium and lamina propria contractions are similar to those observed in detrusor smooth muscle preparations.

Vineesha VeerRuss Chess-WilliamsChristian Moro
Published in: Neurourology and urodynamics (2023)
The data suggests that clinical antimuscarinics are as effective at inhibiting tonic contractions of the U&LP as they are on detrusor, presenting the U&LP as an alternate target of these medications in the treatment of lower urinary tract symptoms.
Keyphrases
  • smooth muscle
  • lower urinary tract symptoms
  • benign prostatic hyperplasia
  • botulinum toxin
  • spinal cord injury
  • signaling pathway
  • electronic health record
  • big data
  • deep learning
  • urinary tract