Fibrinogen promotes malignant biological tumor behavior involving epithelial-mesenchymal transition via the p-AKT/p-mTOR pathway in esophageal squamous cell carcinoma.

Fei ZhangYun WangPeng SunZhi-Qiang WangDe-Shen WangDong-Sheng ZhangFeng-Hua WangJian-Hua FuRui-Hua XuYu-Hong Li

Published in: Journal of cancer research and clinical oncology (2017)

Preoperative plasma hyperfibrinogenemia might serve as an independent predictor of unfavorable survival in ESCC. Furthermore, fibrinogen may promote cell motility by inducing EMT via the p-AKT/p-mTOR pathway.

Keyphrases

epithelial mesenchymal transition
cell proliferation
signaling pathway
transforming growth factor
single cell
patients undergoing
cell therapy
biofilm formation
escherichia coli
staphylococcus aureus
cystic fibrosis
candida albicans