Evaluation of Insulin Lispro Pharmacokinetics and Pharmacodynamics Over 10 Days of Continuous Insulin Infusion in People With Type 1 Diabetes.
Parag GarhyanEdward John PrattOliver KleinSusanne FamullaEric ZijlstraAmy LalondeMonica SwinneyChristof KazdaEyal DassauPublished in: Journal of diabetes science and technology (2022)
The pharmacokinetics of insulin changed over catheter wear time even when an anti-inflammatory agent was present. Postprandial glycemic control was adversely affected by the accelerated insulin absorption and decreased insulin exposure.