Association and Risk Factors of Osteonecrosis of Femoral Head in Sickle Cell Disease: A Systematic Review.
Márcio Passos LeandroCloud Kennedy Couto De SáDiógenes Pires Serra FilhoLucas Azevedo Alves De SouzaCristina SallesMario Cesar Carvalho TenórioCláudio Luiz Da Silva Lima PazMarcos Antônio Almeida MatosPublished in: Indian journal of orthopaedics (2021)
For a better clarification of what the risk factors are for the ONFH, it is necessary to study with populations of different origins, different ages, different profiles of Hb, which present greater methodological rigor and perform a multivariate analysis to control confounding factors. Further study is also needed to understand the genetic determinants of ONFH.