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Epidemiology of Type 3 Poliovirus AFP Cases in Israel between 1973 and 1988: Whole Genome Sequencing of RNA Extracted Directly from Archived Stocks to Avoid Re-Culturing Neurovirulent Wild Poliovirus.

Lester M ShulmanMajid LaassriRachel HandsherTatiana ZagorodnyayaDanit SoferMerav WeilElla MendelsonKonstantin Chumakov
Published in: Vaccines (2022)
Whole or near-whole genome sequence information, obtained from RNA extracted directly from the archived material, safely provided detailed genetic information linked to patient data from a time when limited sequence information was previously available and revealed the pattern of transmission of wild PV3 in Israel.
Keyphrases
  • health information
  • case report
  • genome wide
  • healthcare
  • single cell
  • amino acid
  • copy number