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Osseointegrative effect of rhBMP-2 covalently bound on a titan-plasma-spray-surface after modification with chromosulfuric acid in a large animal bone gap-healing model with the Göttingen minipig.

Manuel LingnerRoland SeidlingLars Johannes LehmannEckhard MauermannUdo ObertackeMarkus Ludwig Rupert Schwarz
Published in: Journal of orthopaedic surgery and research (2018)
BMP-2, covalently bound on a CSA-treated TPS surface, has positive effects on the osseointegration in the large animal bone gap-healing model over the observation period of 12 weeks.
Keyphrases
  • bone mineral density
  • bone regeneration
  • mesenchymal stem cells
  • bone loss