Usefulness of real-time PCR during follow-up of patients treated with Benznidazole for chronic Chagas disease: Experience in two referral centers in Barcelona.
Elena SulleiroAroa SilgadoNúria Serre-DelcorFernando SalvadorMaykon Tavares de OliveiraZaira MoureAugusto Sao-AvilesInés OliveiraBegoña TreviñoLidia GoterrisAdrián Sánchez-MontalváDiana PouIsrael MolinaTomàs PumarolaPublished in: PLoS neglected tropical diseases (2020)
BZ treatment failure was highly infrequent in our cohort. BZ discontinuation was a risk factor for positive real-time PCR results during clinical follow-up. Regular testing with real-time PCR during follow-up allows for early detection of treatment failure in patients with chronic CD.