Inhibitory Effect of Paquinimod on a Murine Model of Neutrophilic Asthma Induced by Ovalbumin with Complete Freund's Adjuvant.
Jong Uk LeeJong Sook ParkJi Ae JunMin Kyung KimHun Soo ChangDong Gyu KimHyun Ji SongMyung-Sin KimChoon-Sik ParkPublished in: Canadian respiratory journal (2021)
These data indicate that paquinimod effectively inhibits neutrophilic inflammation and remodeling in the murine model of neutrophilic asthma, possibly via downregulation of IL-17, IFN-γ, and IL-1β.