Inhibitory Effect of Paquinimod on a Murine Model of Neutrophilic Asthma Induced by Ovalbumin with Complete Freund's Adjuvant.

Jong Uk Lee Jong Sook Park Ji Ae Jun Min Kyung Kim Hun Soo Chang Dong Gyu Kim Hyun Ji Song Myung-Sin Kim Jong-Sook Park

Published in: Canadian respiratory journal (2021)

These data indicate that paquinimod effectively inhibits neutrophilic inflammation and remodeling in the murine model of neutrophilic asthma, possibly via downregulation of IL-17, IFN-γ, and IL-1β.

Keyphrases

chronic obstructive pulmonary disease
lung function
allergic rhinitis
oxidative stress
early stage
immune response
cell proliferation
signaling pathway
big data
cystic fibrosis
air pollution
artificial intelligence