Evaluating the impact of short-term nitrate-rich dietary supplementation on endothelial function in COPD: A randomized crossover study.
Fernanda Beatriz Costa DelacosteCassia da Luz GoulartAugusto Baumhardt GuidotiPatrick TürckBruna EibelMaria Claudia IrigoyenCintia Laura Pereira de AraujoPedro Dal LagoPublished in: Respiratory medicine (2024)
Acute dietary supplementation with nitrates, at the doses provided, did not show a significant improvement in endothelial function assessed by FMD, EndoPAT, or plasma nitrate levels in COPD. These findings suggest that a higher dose or prolonged supplementation might be required to achieve a therapeutic effect.