Development of a clinical scale for assessment of patients with diffuse intrinsic pontine glioma (DIPG) receiving experimental therapy: the PONScore.

Milo Alexander HollingworthStergios Zacharoulis

Published in: Journal of neuro-oncology (2020)

We describe a novel neurological scale that can be used by non-specialists to describe acute neurological changes in children receiving experimental therapy for DIPG. Prospective validation as part of a clinical trial is required.

Keyphrases

clinical trial
liver failure
young adults
low grade
cerebral ischemia
drug induced
study protocol
aortic dissection
double blind
intensive care unit
stem cells
phase iii
mesenchymal stem cells
hepatitis b virus
smoking cessation