Emphysematous change with scleroderma-associated interstitial lung disease: the potential contribution of vasculopathy?
Hideaki YamakawaTamiko TakemuraTae IwasawaYumie YamanakaSatoshi IkedaAkimasa SekineHideya KitamuraTomohisa BabaShinichiro IsoKoji OkudelaKazuyoshi KuwanoTakashi OguraPublished in: BMC pulmonary medicine (2018)
Pulmonary emphysematous changes (LAA within interstitial abnormalities on HRCT and destruction of fibrously thickened alveolar walls) are specific and novel radio-pathological features of SSc-ILD. Peripheral vasculopathy may help to destroy the fibrously thickened alveolar walls, resulting in emphysematous change in SSc-ILD.