Precision Medicine in Type 2 Diabetes: Clinical Markers of Insulin Resistance Are Associated With Altered Short- and Long-term Glycemic Response to DPP-4 Inhibitor Therapy.
John M DennisBeverley M ShieldsAnita V HillBridget A KnightTimothy James McDonaldLauren R RodgersMichael N WeedonWilliam E HenleyNaveed SattarRury R HolmanEwan R PearsonAndrew T HattersleyAngus G Jonesnull nullPublished in: Diabetes care (2018)
Markers of higher insulin resistance are consistently associated with reduced glycemic response to DPP-4 inhibitors. This finding provides a starting point for the application of a precision diabetes approach to DPP-4 inhibitor therapy.