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Population-Based Pharmacokinetics and Dose Optimization of Imipenem in Vietnamese Critically-Ill Patients.

Thanh D DinhHung N NguyenBa Hai LeThuy T T NguyenHuong T L Nguyen
Published in: Infection and drug resistance (2022)
A population pharmacokinetic model of imipenem was developed for Vietnamese adult patients with severe illness. By using Monte Carlo simulation, the appropriate dose has been suggested based on the bacterial MIC value and the targeted PK/PD goal.
Keyphrases
  • monte carlo
  • early onset
  • cancer therapy