First-Line Biological Agents Plus Chemotherapy in Older Patients with Metastatic Colorectal Cancer: A Retrospective Pooled Analysis.

Pilar García AlfonsoEduardo Díaz-RubioAlbert AbadAlfredo CarratoBartomeu MassutíMaría José Ortiz-MoralesJosé Luis Manzano MozoAndrés MuñozGema DuránJavier SastreMaría José SafontReyes FerreiroFernando RiveraEncarnación GonzálezManuel Valladares-AyerbesCristina GrávalosVicente Alonso-OrduñaJosé María ViéitezAlfonso YuberoEnrique Arandanull null

Published in: Drugs & aging (2021)

Biologicals plus chemotherapy is an effective first-line treatment option for selected patients aged ≥ 65 years with mCRC and has a manageable safety profile and efficacy comparable to that observed in younger patients.

Keyphrases

end stage renal disease
newly diagnosed
ejection fraction
chronic kidney disease
prognostic factors
peritoneal dialysis
metastatic colorectal cancer
squamous cell carcinoma
patient reported outcomes
locally advanced
rectal cancer
patient reported