Login / Signup

Associations between low HDL, sex and cardiovascular risk markers are substantially different in sub-Saharan Africa and the UK: analysis of four population studies.

Rosamund GreinerMoffat NyriendaLauren RodgersGershim AsikiLouis BandaBeverly ShieldsAndrew HattersleyAmelia CrampinRobert NewtonAngus G Jones
Published in: BMJ global health (2021)
The relationship between HDL and sex, adiposity and non-HDL cholesterol in sub-Saharan Africa is different from European populations. In sub-Saharan Africans low HDL is a marker of low overall cholesterol and sex differences are markedly attenuated. Therefore low HDL in isolation is unlikely to indicate raised cardiovascular risk and the WHO sex-based cut-offs are inappropriate.
Keyphrases
  • type diabetes
  • metabolic syndrome
  • skeletal muscle
  • adipose tissue
  • low density lipoprotein
  • body mass index