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A double whammy: The association between comorbidities and severe dengue among adult patients-A matched case-control study.

Wei Yao NgRafidah AtanNor'azim Mohd YunosAdam Harrish Bin Md KamalMohd Hariz RoslanKai Yuan QuahKai Xuan TehMasliza ZaidMahazir KassimJeevitha MariapunChin Fang NgimAmreeta DhanoaTsin Wen Yeo
Published in: PloS one (2022)
Our study found a significant association between hypertension and the development of severe dengue in adult patients. For clinical practice, this finding suggests that dengue patients with underlying hypertension warrant closer clinical monitoring for deterioration. The association between significant derangement in various laboratory parameters and severe dengue as shown in this study is in keeping with previous reports. While further substantiation by larger prospective studies will be desirable, this association may serve to inform the dengue triaging process.
Keyphrases
  • zika virus
  • dengue virus
  • aedes aegypti
  • blood pressure
  • clinical practice
  • early onset
  • emergency department
  • drug induced