Higher-order sensorimotor circuit of the whole-brain functional network involved in pruritus regulation in atopic dermatitis.
Haishan WuWenyu DaiZhaoyi HongYue QinMin YangBolun WangJieyue LiaoPublished in: Journal of the European Academy of Dermatology and Venereology : JEADV (2023)
LSFG was involved in pruritus regulation in AD by forming a high-order sensorimotor circuit through the IFOF, a white matter fascicle that proved to provide multimodal integration in motor control and sensory information processing. These results offer more mechanism-guided treatment targets for severe pruritus in AD.