CD36 deficiency ameliorates drug-induced acute liver injury in mice.

Chen ZhangXiao ShiZhongping SuChao HuXianmin MuJinshun PanMengjing LiFengmeng TengTao LingTing ZhaoChe XuGuozhong JiQiang You

Published in: Molecular medicine (Cambridge, Mass.) (2021)

Our data demonstrated that CD36 deficiency ameliorated APAP-induced acute liver injury and inflammatory responses by decreasing JNK activation. CD36 might serve as a new target to reduce acute liver injury.

Keyphrases

drug induced
liver injury
adverse drug
nk cells
signaling pathway
cell death
liver failure
type diabetes
big data
metabolic syndrome
adipose tissue
oxidative stress
machine learning
artificial intelligence
replacement therapy
insulin resistance
high fat diet induced
intensive care unit
mechanical ventilation